For many patients who take too many medications or consider themselves “needle phobic”, topically compounded medications may be the best option for effectively treating most of their problems. Due to compounded medication, podiatric physicians are reluctant to rely on commercialized medications they fear can cause adverse drug interactions and result in denying some patients optimal efforts at pain relief or the reduction of inflammation. Instead, they now have the expanded ability to treat patient problems that are commonly encountered in daily practice.